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Annalisa Camporeale, Francesca Marino, Anna Papageorgiou, Paolo Carai, Sara Fornero, Steven Fletcher, Brent D. G. Page, Patrick Gunning, Marco Forni, Roberto Chiarle, Mara Morello, Ole Jensen, Renzo Levi, Stephane Heymans and Valeria Poli STAT3 activity is necessary and sufficient for the development of immune-mediated myocarditis in mice and promotes progression to dilated cardiomyopathy EMBO Molecular Medicine 5

Version of Record online: 5 MAR 2013 | DOI: 10.1002/emmm.201201876

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Aberrant IL-6/STAT3-mediated induction of liver acute phase response genes including C3, a consequence of pre-existing inflammatory conditions, is involved in determining the degree of myocarditis and its clinical outcome.

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