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Dinah Nockemann, Morgane Rouault, Dominika Labuz, Philip Hublitz, Kate McKnelly, Fernanda C. Reis, Christoph Stein and Paul A. Heppenstall The K+ channel GIRK2 is both necessary and sufficient for peripheral opioid-mediated analgesia EMBO Molecular Medicine 5

Version of Record online: 1 JUL 2013 | DOI: 10.1002/emmm.201201980

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GIRK channels are indispensable for peripheral opioid analgesia. The absence of GIRK channels from mouse dorsal root ganglion neurons questions the predictive validity of mice as a model organism for investigating peripheral GPCRmediated analgesia.

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