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Cindy Fevre, Ana S. Almeida, Solenne Taront, Thierry Pedron, Michel Huerre, Marie-Christine Prevost, Aurélie Kieusseian, Ana Cumano, Sylvain Brisse, Philippe J. Sansonetti and Régis Tournebize A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes EMBO Molecular Medicine 5

Version of Record online: 2 APR 2013 | DOI: 10.1002/emmm.201202023

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Klebsiella rhinoscleromatis causes rhinoscleroma, a neglected infectious lung disease featuring Mikulicz cells, atypical phagocytes containing the bacteria. Maturation of inflammatory monocytes into Mikulicz cells is shown here to be IL-10-dependent.

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