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Anamaria Sudarov, Frank Gooden, Debbie Tseng, Wen-Biao Gan and Margaret Elizabeth Ross Lis1 controls dynamics of neuronal filopodia and spines to impact synaptogenesis and social behaviour EMBO Molecular Medicine 5

Version of Record online: 11 MAR 2013 | DOI: 10.1002/emmm.201202106

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Partial loss of Lis1 causes lissencephaly. Here, the authors show that Lis1 is important for the dynamics of neuronal protrusions in synapse formation and maturation and establish a link between Lis1 gene function and autistic-like behaviors in mice.

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