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Gizem Donmez and Tiago F. Outeiro SIRT1 and SIRT2: emerging targets in neurodegeneration EMBO Molecular Medicine 5

Version of Record online: 18 FEB 2013 | DOI: 10.1002/emmm.201302451

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Sirtuins (SIRTs) are NAD-dependent protein deacetylases, which have been implicated in age-related diseases. This review discusses recent findings on the roles of SIRT1 and SIRT2 in neurodegenerative diseases and in potential therapeutic approaches.

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