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Ayse Ulusoy, Raffaella Rusconi, Blanca I. Pérez-Revuelta, Ruth E. Musgrove, Michael Helwig, Bettina Winzen-Reichert and Donato A. Di Monte Caudo-rostral brain spreading of α-synuclein through vagal connections EMBO Molecular Medicine 5

Version of Record online: 23 MAY 2013 | DOI: 10.1002/emmm.201302475

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α-synuclein lesions spreading in the brain is characteristic of Parkinson's disease and used to stage the disease severity. Here, a new rat model can explain the caudo-rostral pattern of disease progression providing insights into PD pathogenesis.

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