E-mail

E-mail a Wiley Online Library Link

Ana I Arroyo, Paola G Camoletto, Laura Morando, Marco Sassoe-Pognetto, Maurizio Giustetto, Paul P Van Veldhoven, Edward H Schuchman and Maria D Ledesma Pharmacological reversion of sphingomyelin-induced dendritic spine anomalies in a Niemann Pick disease type A mouse model EMBO Molecular Medicine 6

Article first published online: 21 JAN 2014 | DOI: 10.1002/emmm.201302649

Thumbnail image of graphical abstract

A novel pathway is described in a Niemann Pick mouse model whereby elevated sphingomyelin impairs dendritic spines by modulating the actin cytoskeleton. Pharmacological activation of sphingomyelin catabolism in vivo with dexamethasone ameliorates the pathology of affected mice.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

Choose captcha format: Image or Audio. Click here if you need help.

SEARCH