Yi-Cheng Chang, Yu-Hsiang Yu, Jin-Yuh Shew, Wei-Jei Lee, Juey-Jen Hwang, Yen-Hui Chen, Yet-Ran Chen, Pei-Chi Wei, Lee-Ming Chuang and Wen-Hwa Lee Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human EMBO Molecular Medicine 5
Version of Record online: 4 JUL 2013 | DOI: 10.1002/emmm.201302679
Deficiency of the glutathione peroxidase NPGPx increases ROS levels in preadipocytes and promotes adipocyte differentiation via increasing oxidative stress and consequent increased fat mass and adipocyte hypertrophy.
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