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Lorena Pereira, Ana Igea, Begoña Canovas, Ignacio Dolado and Angel R. Nebreda Inhibition of p38 MAPK sensitizes tumour cells to cisplatin-induced apoptosis mediated by reactive oxygen species and JNK EMBO Molecular Medicine 5

Version of Record online: 24 SEP 2013 | DOI: 10.1002/emmm.201302732

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p38alpha/beta inhibition is shown here to sensitize tumor cells to cisplatin-induced apoptosis by increasing ROS levels and activating the JNK pathway, providing an interesting therapeutic strategy of combining p38 inhibitors to anti-cancer drugs.

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