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Gonçalo Regalo and Achim Leutz Hacking cell differentiation: transcriptional rerouting in reprogramming, lineage infidelity and metaplasia EMBO Molecular Medicine 5

Version of Record online: 4 JUL 2013 | DOI: 10.1002/emmm.201302834

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This review discusses cell reprogramming, epithelial metaplasia and hematopoietic lineage ambiguity, and highlights changes in cell fate that occur during tumor initiation leading to discrepancies between tumors phenotype and their cellular origin.

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