Nerea Méndez-Barbero, Vanesa Esteban, Silvia Villahoz, Amelia Escolano, Katia Urso, Arantzazu Alfranca, Cristina Rodríguez, Susana A. Sánchez, Tsuyoshi Osawa, Vicente Andrés, José Martínez-González, Takashi Minami, Juan Miguel Redondo and Miguel R. Campanero A major role for RCAN1 in atherosclerosis progression EMBO Molecular Medicine 5
Article first published online: 15 OCT 2013 | DOI: 10.1002/emmm.201302842
Rcan1 is induced in human and mouse atherosclerotic vessels and found in lesional macrophages, endothelial and vascular smooth muscle cells. Its genetic deletion (or the transplantation of Rcan1-deficient BM-derived cells) reduces the severity of lesions.
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