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Carl Weidinger, Patrick J. Shaw and Stefan Feske STIM1 and STIM2-mediated Ca2+ influx regulates antitumour immunity by CD8+ T cells EMBO Molecular Medicine 5

Version of Record online: 6 AUG 2013 | DOI: 10.1002/emmm.201302989

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Cytotoxic lymphocytes are critical for antitumor immunity. Here, store operated calcium entry (SOCE) mediated by STIM1 and -2 is shown essential to CD8+ T cells antitumor immune responses, arguing against the use of drugs inhibiting SOCE.

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