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Ying-Chang Hsueh, Jasmine M F Wu, Chun-Keung Yu, Kenneth K Wu and Patrick C H Hsieh Prostaglandin E2 promotes post-infarction cardiomyocyte replenishment by endogenous stem cells EMBO Molecular Medicine 6

Version of Record online: 21 JAN 2014 | DOI: 10.1002/emmm.201303687

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Although lost cardiomyocytes could be replenished after injury, the efficiency is extremely low. Here, the authors show that PGE2 treatment at a critical time period improves stem cell-mediated cardiac repair in young mice and restores it in aged animals.

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