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Olena Andrukhova, Svetlana Slavic, Alina Smorodchenko, Ute Zeitz, Victoria Shalhoub, Beate Lanske, Elena E Pohl and Reinhold G Erben FGF23 regulates renal sodium handling and blood pressure EMBO Molecular Medicine 6

Version of Record online: 5 MAY 2014 | DOI: 10.1002/emmm.201303716

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FGF23 serum levels are elevated in chronic kidney disease patients. FGF23 is here shown to be a regulator of the sodium-chloride channel NCC in distal renal tubules, thus affecting renal sodium retention, plasma expansion, hypertension, and heart hypertrophy.

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