Mun-Gwan Hong, Robert Karlsson, Patrik K. E. Magnusson, Matthew R. Lewis, William Isaacs, Lilly S. Zheng, Jianfeng Xu, Henrik Grönberg, Erik Ingelsson, Yudi Pawitan, Corey Broeckling, Jessica E. Prenni, Fredrik Wiklund and Jonathan A. Prince A Genome-Wide Assessment of Variability in Human Serum Metabolism Human Mutation 34
Article first published online: 18 FEB 2013 | DOI: 10.1002/humu.22267
A genome-wide association study of metabolic quantitative traits (mQTLs) was conducted in Swedish men. A global non-targeted metabolite profiling approach was used resulting in the identification of both novel mQTLs and replication of previously described associations. Analyses involving biological pathways and a search for enrichment of mQTLs across the genome highlighted additional novel loci.
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