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Mannis van Oven, Anneleen Van Geystelen, Manfred Kayser, Ronny Decorte and Maarten HD Larmuseau Seeing the Wood for the Trees: A Minimal Reference Phylogeny for the Human Y Chromosome Human Mutation 35

Article first published online: 14 NOV 2013 | DOI: 10.1002/humu.22468

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The continuous incorporation of newly discovered mutations in the ever-expanding human Y-chromosomal phylogenetic tree strongly complicates the task of selecting suitable markers for genotyping purposes in evolutionary, genealogical, medical, and forensic studies. Therefore, we introduce a stable reference phylogeny for the Y chromosome aiming for optimal global discrimination capacity based on a minimal marker set that includes only the most resolving Y-chromosome single-nucleotide polymorphisms. Moreover, we wish to propose a common standard for Y-marker as well as Y-haplogroup nomenclature.

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