Cristina González, Montserrat Torres, Amparo Benito, Jorge del Romero, Carmen Rodríguez, María Fontillón, Mónica Trastoy, Pompeyo Viciana, Julia del Amo, Marta Ortiz, Beatriz Hernández-Novoa and on behalf of the CoRIS-HPV Study Group Anal squamous intraepithelial lesions are frequent among young HIV-infected men who have sex with men followed up at the Spanish AIDS Research Network Cohort (CoRIS-HPV) International Journal of Cancer 133
Anal squamous intraepithelial lesions (SILs) have been implicated as a risk factor for anal cancer in HIV-positive men who have sex with men (MSM), and now, as detailed in this report, it appears that their development is associated with high risk (HR) human papillomavirus (HPV) genotype burden. Analysis of patients enrolled in the Spanish AIDS Research Network Cohort (CoRIS) revealed a seven-fold increase in SIL risk for HIV-positive MSM who had five or more detectable HR-HPV genotypes. The findings could influence the development of SIL screening programs.
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