E-mail a Wiley Online Library Link

Teresa To, Claus Wall, Cornelia J. Baines and Anthony B. Miller Is carcinoma in situ a precursor lesion of invasive breast cancer? International Journal of Cancer 135

Version of Record online: 3 MAR 2014 | DOI: 10.1002/ijc.28803

What's new?

Carcinoma in situ (CIS) is considered to be a precursor of invasive breast cancer, though cumulative breast cancer risk following CIS diagnosis remains uncertain. Here, linking of the Canadian National Breast Screening Study (CNBSS) with cancer registries and a national vital statistics database shows that more than 80% of CNBSS women were free of invasive breast cancer at 20 years post-CIS diagnosis. Little more than 8% had died of breast cancer. The low probability of disease after CIS diagnosis suggests that CIS is not an obligate precursor lesion of invasive breast cancer.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field