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Meena Mahmood, Daniel A. Casciano, Teodora Mocan, Cornel Iancu, Yang Xu, Lucian Mocan, Dana Todea Iancu, Enkeleda Dervishi, Zhongrui Li, Mustafa Abdalmuhsen, Alexandru R. Biris, Nawab Ali, Paul Howard and Alexandru S. Biris Cytotoxicity and biological effects of functional nanomaterials delivered to various cell lines Journal of Applied Toxicology 30

Version of Record online: 16 SEP 2009 | DOI: 10.1002/jat.1475

This research article presents the biological and morphological changes observed in osteocytic and cancer cells after being exposed to various nanomaterials. It has been proved that in a very short time the cells did uptake all the nanomaterials, process which was found to induce changes in the death rates, shapes and sizes of the cells. Moreover, when the nanomaterials were delivered along with chemotherapeutic agents, the cellular death rate increased drastically as compared to the case when the nanomaterials were delivered alone.

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