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Malgorzata M. Brzóska Low-level chronic exposure to cadmium enhances the risk of long bone fractures: a study on a female rat model of human lifetime exposure Journal of Applied Toxicology 32

Version of Record online: 25 JAN 2011 | DOI: 10.1002/jat.1632

It was observed that low lifetime female rats' exposure to cadmium disturbed the mineral status of the femur and tibia resulting in osteopenia or osteoporosis, and enhanced bone fragility. The findings seem to confirm the hypothesis that a low chronic exposure to cadmium may be a risk factor for osteoporosis and fractures of long bones in elderly women and indicate that greater attention should be paid to this toxic metal as an environmental risk factor for osteoporosis and fractures.

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