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Yan-Ping Wang, Qin Hong, Da-ni Qin, Chun-Zhao Kou, Chun-Mei Zhang, Mei Guo, Xi-Rong Guo, Xia Chi and Mei-Ling Tong Effects of embryonic exposure to polychlorinated biphenyls on zebrafish (Danio rerio) retinal development Journal of Applied Toxicology 32

Version of Record online: 7 MAR 2011 | DOI: 10.1002/jat.1650

PCB exposure decreased the survival rate of embryos in a time- and dose-dependent manner. The retinal layer development of zebrafish was delayed at higher PCB concentrations at 72 hpf. Irregularity of photoreceptor cells arrangement and thickening of photoreceptor and ganglionic layers were observed in PCB-treated larvae at concentrations of 0.25–1 mg l−1 at 96 hpf.

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