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R. J. Dearman, D. A. Basketter and I Kimber Inter-relationships between different classes of chemical allergens Journal of Applied Toxicology 33

Version of Record online: 23 JAN 2012 | DOI: 10.1002/jat.1758

Sensitisation of the respiratory tract by chemicals associated with occupational asthma is an important occupational health problem. Here the relationships between skin sensitising chemicals and those that preferentially or exclusively cause respiratory sensitisation is explored. It is demonstrated that chemical respiratory allergens test positive in standard methods for the identification of skin sensitising chemicals, and that this might provide important component of the hazard identification process for these chemicals.

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