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Nalinda Silva, Roshini Peiris-John, Rajitha Wickremasinghe, Hemantha Senanayake and Nalini Sathiakumar Cadmium a metalloestrogen: are we convinced? Journal of Applied Toxicology 32

Version of Record online: 12 DEC 2011 | DOI: 10.1002/jat.1771

Cadmium is a metalloestrogens implicated in the aetiology of oestrogen-dependent diseases. In this review, scientific evidence for the oestrogenic effects of cadmium is critically evaluated to determine if there is sufficient evidence to support cadmium as an aetiological factor of oestrogen-dependent disease in humans. Although the in vitro and in vivo evidence of the oestrogenic properties of cadmium was persuasive, evidence from population-based human studies remain conflicting.

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