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Raymond Poon, Victor E. Valli, W. M. Nimal Ratnayake, Marc Rigden and Guillaume Pelletier Effects of Jatropha oil on rats following 28-day oral treatment Journal of Applied Toxicology 33

Article first published online: 22 DEC 2011 | DOI: 10.1002/jat.1785

Jatropha oil is an emerging feedstock for the production of biodiesels. The increasing use of this non-edible, toxic oil will result in higher potential for accidental exposures. A repeated dose 28-day oral toxicity study was conducted to provide data for risk assessment. It is concluded that Jatropha oil produces adverse effects on female rats starting at 50 mg/kg/day with decreased white blood cell and lymphocyte counts and at 500 mg/kg/day in both genders in term of depressed growth rates.

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