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Soohee Kim and Doug-Young Ryu Silver nanoparticle-induced oxidative stress, genotoxicity and apoptosis in cultured cells and animal tissues Journal of Applied Toxicology 33

Version of Record online: 31 AUG 2012 | DOI: 10.1002/jat.2792

Silver nanoparticles (AgNPs) have emerged as an important class of nanomaterials for a wide range of applications. However, the unique properties of AgNPs could potentially lead to unexpected hazards to human and environmental health. In this study, a number of previous studies are summarized that demonstrate oxidative stress-, genotoxicity- and apoptosis-related changes brought about by AgNPs. The physicochemical properties of AgNPs that are involved in encouraging such changes are also discussed.

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