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M. Nagarajan, V. Maruthanayagam and M. Sundararaman SAR analysis and bioactive potentials of freshwater and terrestrial cyanobacterial compounds: a review Journal of Applied Toxicology 33

Article first published online: 22 NOV 2012 | DOI: 10.1002/jat.2833

Freshwater and terrestrial cyanobacteria produce divergent chemicals including linear, cyclic and azole containing peptides, alkaloids, cyclophanes, terpenes, lactones, etc. These metabolites have wider biomedical potentials in targeting various proteases, cancers, microbes and other cyanobacteria and algae (allelopathy). Besides, studying their broad bioactive spectrum, analyzing the SAR studies will not only assist to find out the mode of action but also reveal bioactive key components. Thereby, developing the drugs bearing these bioactive skeletons to treat various illnesses is wide open.

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