Nicholas Synhaeve, Ndéye Marième Wade-Gueye, Stefania Musilli, Johanna Stefani, Line Grandcolas, Gaëtan Gruel, Maâmar Souidi, Isabelle Dublineau and Jean-Marc Bertho Chronic exposure to low concentrations of strontium 90 affects bone physiology but not the hematopoietic system in mice Journal of Applied Toxicology 34
The effect of chronic ingestion of strontium 90 was investigated in a mouse model, with strontium 90 concentrations representative of environmental contamination after a major nuclear accident. Results did not show evidence for modifications in the hematopoietic system. By contrast, a modification of bone metabolism was demonstrated, but was not linked to phosphocalcic homeostasis. This suggests a direct effect of strontium 90 storage in the bones on osteoblasts and/or osteoclasts.
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