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José G. Dórea, Marcelo Farina and João B. T. Rocha Toxicity of ethylmercury (and Thimerosal): a comparison with methylmercury Journal of Applied Toxicology 33

Version of Record online: 11 FEB 2013 | DOI: 10.1002/jat.2855

EtHg toxicity differs from that of meHg, leading to different toxicity risks. In vitro studies comparing etHg with meHg demonstrate equivalent measured outcomes for cardiovascular, neural, and immune cells. However, distinct toxicokinetic profile between meHg and etHg, results in different compartmental distribution and shorter blood half-life for etHg which can be explained by a faster in vivo dealkylation of etHg than meHg. Immunotoxicity is more pronounced and more common for thimerosal etHg.

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