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Akiko Honda, Yugo Matsuda, Rumiko Murayama, Kenshi Tsuji, Masataka Nishikawa, Eiko Koike, Seiichi Yoshida, Takamichi Ichinose and Hirohisa Takano Effects of Asian sand dust particles on the respiratory and immune system Journal of Applied Toxicology 34

Version of Record online: 9 APR 2013 | DOI: 10.1002/jat.2871

We investigated the effects of Asian sand dust (ASD) particles on respiratory and immune system in vitro. ASD enhanced the production of interleukin (IL)-6, IL-8 and ICAM-1 from human airway epithelial cells, as well as the expression of DEC205 on bone marrow-derived dendritic cells (BMDC) and the proliferation of splenocytes. Moreover, these effects differed partly by ASD events or by components adhered to ASD. These results suggest that ASD can contribute to the respiratory and immune health.

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