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Hong Li, Jin Liu, Yan Sun, Wenxiang Wang, Shaozheng Weng, Shihua Xiao, Huiling Huang and Wenchang Zhang N-hexane inhalation during pregnancy alters DNA promoter methylation in the ovarian granulosa cells of rat offspring Journal of Applied Toxicology 34

Version of Record online: 6 JUN 2013 | DOI: 10.1002/jat.2893

This paper carried out the MeDIP-Chip method to investigate the global genomic promoter methylation status of F1 Wistar rats' Ovarian granulosa cells after maternal n-hexane exposure. The Gene Ontology Consortium, the DAVID Functional Annotation Clustering Tool, hierarchical clustering, and KEGG pathway were used to delineate the altered methylation of promoters of gene and find out the gene-enriched clusters.

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