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Julie E. Goodman, Robyn L. Prueitt, Juhi Chandalia and Sonja N. Sax Evaluation of adverse human lung function effects in controlled ozone exposure studies Journal of Applied Toxicology 34

Version of Record online: 9 JUL 2013 | DOI: 10.1002/jat.2905

We examined the concentration of ozone at which lung function decrements are observed and should be considered adverse in recent controlled human exposure studies using the Adverse Effects/Causation Framework. Below 72 ppb, lung function effects are primary effects, but are isolated, independent, and not statistically significant (i.e., not casual). Up to 72 ppb, lung function effects are transient, reversible, and of low severity (i.e., not adverse). This supports the current National Ambient Air Quality Standard of 75 ppb.

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