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Matthew J. Barton, John W. Morley, Marcus A. Stoodley, Sumaiya Shaikh, David A. Mahns and Antonio Lauto Long term recovery of median nerve repair using laser-activated chitosan adhesive films Journal of Biophotonics 8

Version of Record online: 17 OCT 2013 | DOI: 10.1002/jbio.201300129

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Sutures remain the standard peripheral nerve repair technique, whether applied directly or indirectly to nerve tissue. Photochemical-tissuebonding (PTB) using rose Bengal (RB) integrated into a chitosan bioadhesive is an alternative nerve repair device that removes the need for sutures. RB-chitosan adhesive repaired nerves displayed comparable results when compared to the standard suture-repair based on histological and electrophysiological findings. Functionally, RB-chitosan adhesive was associated with a quicker and more pronounced recovery of grip force when compared to the suture-repair.

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