Zeinab Hajjarian, Markandey M. Tripathi and Seemantini K. Nadkarni Optical Thromboelastography to evaluate whole blood coagulation Journal of Biophotonics 8
Optical Thromboelastography (OTEG) is a novel diagnostic technology for quantifying blood coagulation status in patients. OTEG evaluates laser speckle fluctuations, reflected from a few drops of blood. Spatio-temporal speckle analyses yield 2-dimensional viscoelasticity maps, visualizing incipient micro-clot formation at distinct rates in normal and coagulopathic patients. These findings demonstrate the exquisite sensitivity and accuracy of OTEG in diagnosing coagulopathies within a few minutes and highlights the potential for point-of-care use.
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