E-mail

E-mail a Wiley Online Library Link

Susanne Pape, Franziska Hoffgaard, Mirjam Dür and Kay Hamacher Distance dependency and minimum amino acid alphabets for decoy scoring potentials Journal of Computational Chemistry 34

Version of Record online: 1 SEP 2012 | DOI: 10.1002/jcc.23099

Thumbnail image of graphical abstract

Protein structure is determined by amino acid interactions and thus sequence specific. The 3D-fold of a protein gives rise to distance-dependent interactions of the amino acids. In this article, the full distance dependency is derived by formulating the underlying modeling problem as a linear program. Upon solving this optimization problem for the full or reduced amino acid alphabets, one obtains new insight into structure threading and protein evolution.

Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf

Required = Required Field

SEARCH