A. Pacelli, J. Greenman, C. Cawthorne and G. Smith Imaging COX-2 expression in cancer using PET/SPECT radioligands: current status and future directions Journal of Labelled Compounds and Radiopharmaceuticals 57
Radiolabelled cyclooxygenase-2 probes have been the focus of considerable interest over the last few years, but progress to optimal imaging agents has been slow. This is in large part a result of the challenging nature of the target and the local tumour microenvironment. This review summarises the most recent developments in the area.
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