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A. C. Baclig, T. C. Bakker Schut, G. M. O'Regan, A. D. Irvine, W. H. I. McLean, G. J. Puppels and P. J. Caspers Possibilities for human skin characterization based on strongly reduced Raman spectroscopic information Journal of Raman Spectroscopy 44

Version of Record online: 17 FEB 2013 | DOI: 10.1002/jrs.4198

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It is demonstrated that relevant clinical information about the human skin can be extracted from Raman spectra with substantially reduced spectral information. By using the integrated intensities of only four carefully selected spectral regions, discrimination of skin with low natural moisturizing factor (NMF) content from skin with normal NMF content with high accuracy is demonstrated. This simplified detection of Raman signal can be exploited to decrease the complexity and cost of Raman instrumentation for the identification of people with increased risk of developing atopic dermatitis.

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