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Mehmet Fatih Canbolat, Christina Tang, Susan H. Bernacki, Behnam Pourdeyhimi and Saad Khan Mammalian Cell Viability in Electrospun Composite Nanofiber Structures Macromolecular Bioscience 11

Article first published online: 25 AUG 2011 | DOI: 10.1002/mabi.201100108

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We study two approaches to incorporate live mammalian cells into nanofibrous structures, cell electrospinning, and cell layering. While cells die in cell electrospinning, most survive cell layering. Fiber stretching and dehydration are the main factors affecting cell viability in cell electrospinning. In cell layering, residual solution affects cell viability; highest viability occurs using HFIP.

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