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Xiao-Ding Xu, Bing-Bing Lin, Jun Feng, Ya Wang, Si-Xue Cheng, Xian-Zheng Zhang and Ren-Xi Zhuo Biological Glucose Metabolism Regulated Peptide Self-Assembly as a Simple Visual Biosensor for Glucose Detection Macromolecular Rapid Communications 33

Article first published online: 9 FEB 2012 | DOI: 10.1002/marc.201100689

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Peptide building blocks with self-assembly ability which could be regulated by a biological glucose metabolism were designed and synthesized. As the metabolic product, gluconic acid can trigger the protonation of peptide and induce phase transition. Because the glucose metabolism regulated self-assembly is based on the oxidation of glucose, it can be used as a visual biosensor for glucose detection.

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