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Shujuan Liu, Weili Qiao, Guoyi Cao, Yang Chen, Yun Ma, Yanqin Huang, Xiangmei Liu, Wenjuan Xu, Qiang Zhao and Wei Huang Smart Poly(N-isopropylacrylamide) Containing Iridium(III) Complexes as Water-Soluble Phosphorescent Probe for Sensing and Bioimaging of Homocysteine and Cysteine Macromolecular Rapid Communications 34

Article first published online: 12 OCT 2012 | DOI: 10.1002/marc.201200589

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An excellent phosphorescent bioprobe based on iridium(III) complex-functionalized poly(N-isopropylacrylamide) for the detection of Hcy and Cys is designed and synthesized. Sensitive detection of Hcy and Cys in an aqueous system is realized and successfully applied in bioimaging within living cells. The phosphorescent hydrogel is also synthesized, which realizes nakedeye detection for Hcy and Cys.

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