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Sanjay J. Mathew, Xiangling Mao, Kathryn A. Keegan, Susan M. Levine, Eric L. P. Smith, Linda A. Heier, Viktor Otcheretko, Jeremy D. Coplan and Dikoma C. Shungu Ventricular cerebrospinal fluid lactate is increased in chronic fatigue syndrome compared with generalized anxiety disorder: an in vivo 3.0 T 1H MRS imaging study NMR in Biomedicine 22

Version of Record online: 21 OCT 2008 | DOI: 10.1002/nbm.1315

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Lactate was found to be significantly elevated in the lateral ventricular cerebrospinal fluid of patients with chronic fatigue syndrome compared with patients with generalized anxiety disorder or with healthy control subjects, a finding that remained significant even after adjusting for lateral ventricular volume, which did not differ between the three groups.

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