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B. A. Taylor, A. M. Elliott, K. P. Hwang, J. D. Hazle and R. J. Stafford Correlation between the temperature dependence of intrinsic MR parameters and thermal dose measured by a rapid chemical shift imaging technique NMR in Biomedicine 24

Article first published online: 1 JUL 2011 | DOI: 10.1002/nbm.1707

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Temperature-dependent changes in the proton resonance frequency, R2*, and T1-W amplitudes were measured simultaneously in ex vivo tissue heated with a 980-nm laser at 1.5T and 3.0T. Changes in the temperature sensitivity of R2* and, in some instances, T1-W amplitudes were found to be correlated with damage predicted by an Arrhenius dose rate model.

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