Barbara Ganisl and Dr. Kathrin Breuker Does Electron Capture Dissociation Cleave Protein Disulfide Bonds? ChemistryOpen 1
Runner-up! Disulfide bond cleavage comes second in gas phase radical ion chemistry. Cleavage of NCα backbone bonds is preferred over disulfide bond cleavage in electron capture dissociation (ECD) of peptides and proteins, but disulfide bonds can be cleaved by vibrational excitation or secondary radical reactions.
Complete the form below and we will send an e-mail message containing a link to the selected article on your behalf