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Christian N. Paxton, Arthur R. Brothman and Katherine B. Geiersbach Rapid aneusomy detection in products of conception using the KaryoLite™ BACs-on-Beads™ assay Prenatal Diagnosis 33

Version of Record online: 8 NOV 2012 | DOI: 10.1002/pd.4003

What's already known about this topic?

  • The KaryoLite™ BACs-on-Beads™ assay utilizes the same technology as the Prenatal BACs-on-Beads™ assay.
  • KaryoLite™ is designed to detect aneusomy for all chromosomes (1–22, X, and Y).

What does this study add?

  • Successful in detecting aneusomy in samples where failed cultures prevent karyotyping.
  • Identifies approximately three fourths of all abnormalities observed in products of conception in our laboratory.

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