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Heather Skirton and Christine Patch Factors affecting the clinical use of non-invasive prenatal testing: a mixed methods systematic review Prenatal Diagnosis 33

Version of Record online: 4 APR 2013 | DOI: 10.1002/pd.4094

What's already known about this topic?

  • Non-invasive prenatal testing (NIPT) is available for foetal sex determination in pregnancies at high risk of sex-linked disorders and for diagnosis of a limited number of genetic conditions.
  • There is limited use of NIPT for aneuploidy detection, albeit currently only in the private sector.
  • This method eliminates the risks to the foetus inherent in invasive procedures and can be performed earlier in the pregnancy.

What does this study add?

  • Users and potential users of NIPT regard it positively, but there are wider ethical and societal concerns about the impact of easier access to prenatal testing.

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