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Shilpa Chetty, Matthew J. Garabedian and Mary E. Norton Uptake of noninvasive prenatal testing (NIPT) in women following positive aneuploidy screening Prenatal Diagnosis 33

Article first published online: 17 MAY 2013 | DOI: 10.1002/pd.4125

What's already known about this topic?

  • NIPT now offers an alternative to invasive diagnostic testing in the setting of positive screening results, with high sensitivity and specificity for trisomies 18 and 21.

What does this study add?

  • The introduction of NIPT in our population has influenced the prenatal diagnostic choices made by women with abnormal aneuploidy screening. We found that rates of invasive testing decreased significantly following the introduction of NIPT. Additionally, fewer women declined follow-up testing when NIPT was an option.

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