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Diana W. Bianchi, Dick Oepkes and Alessandro Ghidini Current controversies in prenatal diagnosis 1: should noninvasive DNA testing be the standard screening test for Down syndrome in all pregnant women? Prenatal Diagnosis 34

Article first published online: 24 SEP 2013 | DOI: 10.1002/pd.4229

What's already known about this topic?

  • Noninvasive DNA testing (NIDT) is recommended in many developed countries as an option for pregnant women who have already been determined to be at high risk for fetal aneuploidy.
  • Over 2 years of clinical experience has been accumulated with offering NIDT as an advanced screen for fetal autosomal aneuploidy.
  • At the present time, most testing is being performed by commercial organizations.

What does this study add?

  • This study provides a written transcript to accompany an oral debate that was presented at the 17th International Conference on Prenatal Diagnosis and Therapy in Lisbon, Portugal, on 3 June 2013.
  • The debaters, who are both experts in maternal–fetal medicine, consider the benefits and limitations of offering NIDT to all pregnant women regardless of their a priori risk of having a fetus with a chromosome abnormality.

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