Eric Hildebrand, Bengt Källén, Ann Josefsson, Tomas Gottvall and Marie Blomberg Maternal obesity and risk of Down syndrome in the offspring Prenatal Diagnosis 34
What's already known about this topic?
- A combination of ultrasound and biochemistry is a well-studied method for risk assessment of fetal aneuploidy.
What does this study add?
- Maternal obesity in very early pregnancy is associated with increased risk for Down syndrome in the newborn.
- Combined first trimester screening for aneuploidies is equally effective for all body mass index categories.
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