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Ho-Seok Kwak, Jung-Yeol Han, June-Seek Choi, Hyun-Kyong Ahn, Dong-Wook Kwak, Yeon-Kyung Lee, Sun-Young Koh, Go-Un Jeong, E. Yadira Velázquez-Armenta and Alejandro A. Nava-Ocampo Dose-response and time-response analysis of total fatty acid ethyl esters in meconium as a biomarker of prenatal alcohol exposure Prenatal Diagnosis 34

Version of Record online: 13 MAY 2014 | DOI: 10.1002/pd.4374

What's already known about this topic?

  • Normal fetal neurodevelopment can be severely affected by prenatal alcohol exposure. Increased cumulative levels of fatty acids ethyl esters in meconium are considered as reliable biomarkers of prenatal alcohol exposure and may help to identify babies at risk of ethanol-related birth defects.

What does this study add?

  • Although fatty acids ethyl esters are unquestionable non-oxidative metabolites of alcohol, their cumulative concentration cannot be considered as a reliable biomarker of light-to-moderate prenatal alcohol exposure.

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