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Jian-Je Chen, Quoc-Phong Ho and Meng-Jiy Wang Modulation of cell responses by creating surface submicron topography and amine functionalities Journal of Polymer Science Part B: Polymer Physics 50

Version of Record online: 27 DEC 2011 | DOI: 10.1002/polb.23024

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A facile method to fabricate polystyrene-co-maleic anhydride (PSMAA) exhibiting well-ordered submicron pores by phase-separation and spin coating method is reported. The nanostructured PSMAA is further functionalized by dopamine blending or by nitrogen/hydrogen plasma treatments. The results show that the creation of a microenvironment and the integration of chemical functionalities provide promising effects for promoting the growth of mammalian cells.

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