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Jayant J. Khandare, Archana Jalota-Badhwar, Neetika Taneja, Russel R. Mascarenhas, Karan Vadodaria, Khushbu R. Zope and Shashwat S. Banerjee Fabrication of pH-Tunable Calcium Phosphate Nanocapsules via Dendrimer-Templated Assembly for Intracellular Lysosomal Release of Drugs Particle & Particle Systems Characterization 30

Article first published online: 22 MAR 2013 | DOI: 10.1002/ppsc.201300034

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A pH-responsive dendrimer templated polymer-calcium phosphate core shell nanostructure is developed. Upon exposure to cellular lysosomal pH, a guest anticancer drug is released from the nanocapsule by dissolution of the CaP shell. Such a stimuli responsive carrier enables on-demand controlled release of drugs in acidic organelles.

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